Hexylresorcinol AF (e.q. Hentowhite)
- Product Code: 125958
a water soluble version of 4-Hexylresorcinol, is an alkylresorcinol with many skin benefits
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| Test Name | Specification |
|---|---|
| ASPECT | Syrup |
| COLOUR | Amber |
| MICROBIOLOGICAL CONTROL | < 50 CFU/g (Total germs) |
| MICROBIOLOGICAL CONTROL (Pathogens) | Absence |
| ULTRA-VIOLET SPECTRUM | (Alcohol sol. 0.05%) Conforms to standard |
| INFRA-RED SPECTRUM | Conforms to standard |
| REFRACTIVE INDEX (20 | 1.465-1.485 |
| DENSITY (20 | 0.980-1.200 g/ml |
| ACIDITY INDEX | 15.00-25.00 mg KOH/g |
| PEROXIDE INDEX | 10.00 meq O2/kg Max |
| IODINE INDEX (Wij) | 20.00-35.00 gl2/100 g |
| SOLUBILITY (Ethanol) | Transparent solution |
| SOLUBILITY (Glycerin or Propylene Glycol) | Whitish solution |
| SOLUBILITY (Water) | Transparent solution |
Hexylresorcinol AF is a water soluble version of 4-Hexylresorcinol, is an alkylresorcinol with many skin benefits:
- Whitening Care
- Age-spot treatment
- Photo-aging, brightening/lightening Care
- Underarm and bikini area spots
- Ethnic skin Care
Description:
Hexylresorcinol AF is a naturally effective cosmetic ingredient for the reduction of skin dark spots and skin whitening, without irritation effects. It has a significant reducing effect on tyrosinase activity and works synergistically on the three stages of the melanogenesis process:
- Before melanin synthesis: Interferes in the synthesis and glycosylation of tyrosinase, preventing its absorption by the melanosome.
- During melanin synthesis: Acts as a competitive inhibitor of tyrosinase, also affecting TRP1 and TRP2 enzymes, reducing melanogenesis-promoting byproducts.
- After melanin synthesis: Enhances tyrosinase degradation, inhibits melanosome transfer to keratinocytes, and offers light peeling thanks to the fatty acids.
Benefits:
- Decreases melanin formation at the early stage of synthesis
- Reduces melanin synthesis and tyrosinase activity in skin melanocytes
- Reduces melanosome transfer to keratinocytes
- Promotes desquamation of superficial horny layers and melanin pigmentary residues
- Non-irritating effect
Clinical Efficacy Tests:
1. Whitening Effect:
Melanin synthesis inhibition vs Hydroquinone on melanocyte cell culture.
2. Tyrosinase Inhibition:
Spectrophotometric assay vs Kojic acid and Hydroquinone - 100% inhibition at 0.001%.
3. In-Vivo Whitening Efficacy:
20 volunteers, T=4 weeks - 94.6% inhibition (0.15 mg/L Hexylresorcinol AF).
Usage: Ingredients in any whitening formulation
Mixing method: Soluble in water
Usage rate: 1-3%
Product characteristics: Clear transparent light colored liquid
Solubility: Can dissolve in water
Storage: Shelf life: 24 months, stored at cold temperature. Avoid sunlight and heat.
INCI Name : Polysorbate 20, Hexylresorcinol, Caprylic Acid, Isopropyl alcohol, Peg-400, Caproic Acid, Capric Acid.
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Hexylresorcinol AF (e.q. Hentowhite)
a water soluble version of 4-Hexylresorcinol, is an alkylresorcinol with many skin benefits
Hexylresorcinol AF is a water soluble version of 4-Hexylresorcinol, is an alkylresorcinol with many skin benefits:
- Whitening Care
- Age-spot treatment
- Photo-aging, brightening/lightening Care
- Underarm and bikini area spots
- Ethnic skin Care
Description:
Hexylresorcinol AF is a naturally effective cosmetic ingredient for the reduction of skin dark spots and skin whitening, without irritation effects. It has a significant reducing effect on tyrosinase activity and works synergistically on the three stages of the melanogenesis process:
- Before melanin synthesis: Interferes in the synthesis and glycosylation of tyrosinase, preventing its absorption by the melanosome.
- During melanin synthesis: Acts as a competitive inhibitor of tyrosinase, also affecting TRP1 and TRP2 enzymes, reducing melanogenesis-promoting byproducts.
- After melanin synthesis: Enhances tyrosinase degradation, inhibits melanosome transfer to keratinocytes, and offers light peeling thanks to the fatty acids.
Benefits:
- Decreases melanin formation at the early stage of synthesis
- Reduces melanin synthesis and tyrosinase activity in skin melanocytes
- Reduces melanosome transfer to keratinocytes
- Promotes desquamation of superficial horny layers and melanin pigmentary residues
- Non-irritating effect
Clinical Efficacy Tests:
1. Whitening Effect:
Melanin synthesis inhibition vs Hydroquinone on melanocyte cell culture.
2. Tyrosinase Inhibition:
Spectrophotometric assay vs Kojic acid and Hydroquinone - 100% inhibition at 0.001%.
3. In-Vivo Whitening Efficacy:
20 volunteers, T=4 weeks - 94.6% inhibition (0.15 mg/L Hexylresorcinol AF).
Usage: Ingredients in any whitening formulation
Mixing method: Soluble in water
Usage rate: 1-3%
Product characteristics: Clear transparent light colored liquid
Solubility: Can dissolve in water
Storage: Shelf life: 24 months, stored at cold temperature. Avoid sunlight and heat.
INCI Name : Polysorbate 20, Hexylresorcinol, Caprylic Acid, Isopropyl alcohol, Peg-400, Caproic Acid, Capric Acid.
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