Fmoc-D-HoPhe-OH
97%
- Product Code: 97519
CAS:
135944-09-1
| Molecular Weight: | 401.45 g./mol | Molecular Formula: | C₂₅H₂₃NO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00151917 | |
| Melting Point: | Boiling Point: | 628.3°C | |
| Density: | Storage Condition: | room temperature, dry |
Product Description:
This chemical is primarily used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) methods. It serves as a protected amino acid derivative, where the Fmoc (fluorenylmethyloxycarbonyl) group acts as a temporary protecting group for the amine functionality during the peptide chain assembly. The D-HoPhe (D-homophenylalanine) moiety is a non-natural amino acid that can be incorporated into peptides to modify their structure, stability, or biological activity.
Its application is significant in the development of peptide-based drugs, where the incorporation of non-natural amino acids like D-HoPhe can enhance the peptide's resistance to enzymatic degradation, improve pharmacokinetic properties, or alter receptor binding specificity. This compound is also valuable in research for studying peptide-protein interactions and designing peptide mimetics for therapeutic or diagnostic purposes.
Additionally, it is used in the synthesis of peptidomimetics and bioactive peptides, which are explored for their potential in treating diseases such as cancer, infections, and metabolic disorders. Its role in peptide chemistry makes it a crucial tool in both academic research and pharmaceutical development.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | ฿270.00 |
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| 1.000 | 10-20 days | ฿450.00 |
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| 5.000 | 10-20 days | ฿1,962.00 |
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| 25.000 | 10-20 days | ฿7,920.00 |
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Fmoc-D-HoPhe-OH
This chemical is primarily used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) methods. It serves as a protected amino acid derivative, where the Fmoc (fluorenylmethyloxycarbonyl) group acts as a temporary protecting group for the amine functionality during the peptide chain assembly. The D-HoPhe (D-homophenylalanine) moiety is a non-natural amino acid that can be incorporated into peptides to modify their structure, stability, or biological activity.
Its application is significant in the development of peptide-based drugs, where the incorporation of non-natural amino acids like D-HoPhe can enhance the peptide's resistance to enzymatic degradation, improve pharmacokinetic properties, or alter receptor binding specificity. This compound is also valuable in research for studying peptide-protein interactions and designing peptide mimetics for therapeutic or diagnostic purposes.
Additionally, it is used in the synthesis of peptidomimetics and bioactive peptides, which are explored for their potential in treating diseases such as cancer, infections, and metabolic disorders. Its role in peptide chemistry makes it a crucial tool in both academic research and pharmaceutical development.
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