SB431542
≥98%
- Product Code: 77769
CAS:
301836-41-9
| Molecular Weight: | 384.39 g./mol | Molecular Formula: | C₂₂H₁₆N₄O₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD05865244 | |
| Melting Point: | 214°C | Boiling Point: | |
| Density: | Storage Condition: | -20°C |
Product Description:
SB431542 is widely used in biological research to inhibit the TGF-β signaling pathway. It specifically targets and blocks the activity of TGF-β type I receptors, ALK4, ALK5, and ALK7. This inhibition is crucial in studies focused on understanding cellular processes such as differentiation, proliferation, and apoptosis. Researchers frequently employ SB431542 to maintain pluripotency in stem cell cultures, as it prevents differentiation induced by TGF-β signaling. Additionally, it is utilized in cancer research to study the role of TGF-β in tumor progression and metastasis. Its ability to modulate TGF-β pathways also makes it valuable in fibrosis research, where it helps in exploring potential therapeutic strategies. Overall, SB431542 is a key tool in elucidating the complex roles of TGF-β signaling in various biological contexts.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | Light yellow to yellow solid |
| PURITY | 98-100 |
| NMR | Consistent with structure |
| Infrared spectrum | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.010 | 10-20 days | ฿1,980.00 |
+
-
|
| 0.050 | 10-20 days | ฿6,420.00 |
+
-
|
| 0.100 | 10-20 days | ฿10,800.00 |
+
-
|
SB431542
SB431542 is widely used in biological research to inhibit the TGF-β signaling pathway. It specifically targets and blocks the activity of TGF-β type I receptors, ALK4, ALK5, and ALK7. This inhibition is crucial in studies focused on understanding cellular processes such as differentiation, proliferation, and apoptosis. Researchers frequently employ SB431542 to maintain pluripotency in stem cell cultures, as it prevents differentiation induced by TGF-β signaling. Additionally, it is utilized in cancer research to study the role of TGF-β in tumor progression and metastasis. Its ability to modulate TGF-β pathways also makes it valuable in fibrosis research, where it helps in exploring potential therapeutic strategies. Overall, SB431542 is a key tool in elucidating the complex roles of TGF-β signaling in various biological contexts.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Cart
No products
Subtotal:
฿0.00
฿0.00
Total :