special type of Collagen Tri-Peptide that tested and found to have very high skin benefits

Minimum Collagen Tri-peptide > 30%

Health Benefits of Collagen Tri-Peptides from Fish

Collagen Tri-Peptides (CTPs) are small, bioactive peptides consisting of three amino acids derived from the hydrolysis of collagen protein. Fish collagen, in particular, is known for its high absorption rate due to its low molecular weight.

WrinkleCare™ Collagen Tri-Peptide (High Elastin) is a special type of Collagen Tri-Peptide that tested and found to have the following skin benefits:

1. High anti-elastase effect which will stop the skin's elastase degradation. More than 65% of elastase degradation can be stopped at 50mg/ml concentration

2. High anti-hyaluronidase effect which will stop the skin's hyaluron degradation. More than 50% of hyaluron degradation can be stopped at 50mg/ml concentration

3. High anti-oxidant property based on DPPH assay. More than 40% of oxidation can be stopped at 50mg/ml concentration

The company offers lab service that can test these activities in your finished product

1. Skin Health

Improved Skin Elasticity and Reduction of Wrinkles

CTPs can promote skin health by stimulating the synthesis of collagen and elastin fibers, leading to improved skin elasticity, hydration, and a reduction in wrinkles.

• Citation: Matsumoto, H., Ohara, H., Ito, K., Nakamura, Y., & Takahashi, S. (2006). Clinical effects of fish type I collagen hydrolysate on skin properties. Journal of Nutritional Science and Vitaminology, 52(3), 211-215

2. Joint Health

Alleviation of Joint Pain and Cartilage Regeneration

Fish-derived CTPs may help reduce joint pain and support cartilage regeneration by supplying essential amino acids that stimulate chondrocyte activity.

• Citation: Bello, A. E., & Oesser, S. (2006). Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders: a review of the literature. Current Medical Research and Opinion, 22(11), 2221-2232

3. Bone Health

Enhancement of Bone Mineral Density

CTPs can promote bone health by increasing bone mineral density and supporting the activity of osteoblasts, the cells responsible for bone formation.

• Citation: Wu, J., Fujioka, M., Sugimoto, K., Mu, G., & Ishimi, Y. (2004). Assessment of effectiveness of oral administration of collagen peptide on bone metabolism in growing and mature rats. Journal of Bone and Mineral Metabolism, 22(6), 547-553. DOI: 10.1007/s00774-004-0522-0

4. Antioxidant Properties

Neutralization of Free Radicals

Fish collagen tri-peptides exhibit antioxidant activities that help neutralize free radicals, thereby reducing oxidative stress and potential cellular damage.

• Citation: Liu, D., Nikoo, M., Boran, G., Zhou, P., & Regenstein, J. M. (2015). Collagen and gelatin. Annual Review of Food Science and Technology, 6, 527-557

5. Wound Healing

Accelerated Tissue Repair

CTPs may enhance wound healing by promoting the migration and proliferation of fibroblasts, cells essential for tissue repair and collagen synthesis.

• Citation: Nishimoto, S., Katayama, K., Ishikawa, H., & Hayashi, Y. (2013). The effect of collagen peptide ingestion on wound healing. The Journal of Veterinary Medical Science, 75(11), 1541-1544

6. Muscle Mass Preservation

Support for Muscle Protein Synthesis

Fish collagen tri-peptides may aid in preserving muscle mass by providing essential amino acids necessary for muscle protein synthesis, beneficial for aging populations.

• Citation: Iwai, K., Hasegawa, T., Taguchi, Y., Morimatsu, F., Sato, K., Nakamura, Y., ... & Oda, H. (2005). Identification of food-derived collagen peptides in human blood after oral ingestion of gelatin hydrolysates. Journal of Agricultural and Food Chemistry, 53(16), 6531-6536