Tirzepatide

  • Product Code: 125797

a medication primarily used to treat type 2 diabetes. It is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, meaning it mimics the effects of these two hormones to help regulate blood sugar levels.

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Test Name Specification
Appearance White or almost white loose powder or lumps
Solubility Freely soluble in water, 50% Acetonitrile and DMSO
Specific rotation [?]20D -20.0° to -35.0° (anhydrous and sodium ion-free basis)
Identification by HPLC The retention time of the principal peak of the test solution corresponds to that of the reference solution, as obtained in the
Identification by MS 4812.5 - 4814.5
Amino acid content: Ser 4.5-5.5
Amino acid content: Gly 3.6-4.4
Amino acid content: Asp 1.8-2.2
Amino acid content: Glu 3.6-4.4
Amino acid content: Thr 1.8-2.2
Amino acid content: Ala 3.6-4.4
Amino acid content: Pro 3.6-4.4
Amino acid content: Aib 1.8-2.2
Amino acid content: Lys 1.8-2.2
Amino acid content: Tyr 1.8-2.2
Amino acid content: Val 0.9-1.1
Amino acid content: Ile 2.7-3.3
Amino acid content: Leu 1.8-2.2
Amino acid content: Phe 1.8-2.2
Amino acid content: Trp Should be detected
AEEA Should be detected
Water Content (K.F) NMT 8.0%
pH Should be 5.5 to 8.0
Clarity and color of solution Clear and colorless

Tirzepatide is a medication primarily used to treat type 2 diabetes. It is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, meaning it mimics the effects of these two hormones to help regulate blood sugar levels. Here are some of the main health benefits associated with Tirzepatide:

1. Improved Blood Sugar Control

  • Mechanism: Tirzepatide enhances insulin secretion in response to meals, reduces glucagon secretion (which decreases glucose production by the liver), and slows gastric emptying, all of which contribute to lowering blood glucose levels.
  • Effectiveness: Clinical trials have shown that Tirzepatide significantly lowers HbA1c levels (a measure of long-term blood glucose control), often more effectively than other diabetes medications, including some GLP-1 receptor agonists.

2. Weight Loss

  • Mechanism: Tirzepatide helps to reduce appetite and calorie intake, likely through its action on the brain's appetite regulation centers. It also slows gastric emptying, which can increase feelings of fullness.
  • Effectiveness: Patients taking Tirzepatide have experienced significant weight loss. In some studies, weight loss was greater than that achieved with GLP-1 receptor agonists alone.

3. Cardiovascular Benefits

  • Mechanism: By improving blood glucose control and aiding in weight loss, Tirzepatide may reduce the risk of cardiovascular diseases, which are common complications in people with type 2 diabetes.
  • Effectiveness: Early data suggests Tirzepatide may have positive effects on cardiovascular risk factors, such as lowering blood pressure and improving lipid profiles, although more long-term studies are needed to fully understand its impact on cardiovascular outcomes.

4. Potential Benefits for Non-Diabetic Individuals

  • Weight Management: Emerging research suggests Tirzepatide might be beneficial for weight management in non-diabetic individuals due to its significant impact on weight loss.
  • Prediabetes Management: Tirzepatide may also help prevent the progression from prediabetes to type 2 diabetes, given its ability to improve glucose metabolism and reduce insulin resistance.

5. Improved Quality of Life

  • Overall Well-being: Patients using Tirzepatide often report an improved quality of life due to better control over blood sugar levels, weight loss, and potentially reduced medication burden if Tirzepatide can replace other diabetes medications.



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Tirzepatide

a medication primarily used to treat type 2 diabetes. It is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, meaning it mimics the effects of these two hormones to help regulate blood sugar levels.

Tirzepatide is a medication primarily used to treat type 2 diabetes. It is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, meaning it mimics the effects of these two hormones to help regulate blood sugar levels. Here are some of the main health benefits associated with Tirzepatide:

1. Improved Blood Sugar Control

  • Mechanism: Tirzepatide enhances insulin secretion in response to meals, reduces glucagon secretion (which decreases glucose production by the liver), and slows gastric emptying, all of which contribute to lowering blood glucose levels.
  • Effectiveness: Clinical trials have shown that Tirzepatide significantly lowers HbA1c levels (a measure of long-term blood glucose control), often more effectively than other diabetes medications, including some GLP-1 receptor agonists.

2. Weight Loss

  • Mechanism: Tirzepatide helps to reduce appetite and calorie intake, likely through its action on the brain's appetite regulation centers. It also slows gastric emptying, which can increase feelings of fullness.
  • Effectiveness: Patients taking Tirzepatide have experienced significant weight loss. In some studies, weight loss was greater than that achieved with GLP-1 receptor agonists alone.

3. Cardiovascular Benefits

  • Mechanism: By improving blood glucose control and aiding in weight loss, Tirzepatide may reduce the risk of cardiovascular diseases, which are common complications in people with type 2 diabetes.
  • Effectiveness: Early data suggests Tirzepatide may have positive effects on cardiovascular risk factors, such as lowering blood pressure and improving lipid profiles, although more long-term studies are needed to fully understand its impact on cardiovascular outcomes.

4. Potential Benefits for Non-Diabetic Individuals

  • Weight Management: Emerging research suggests Tirzepatide might be beneficial for weight management in non-diabetic individuals due to its significant impact on weight loss.
  • Prediabetes Management: Tirzepatide may also help prevent the progression from prediabetes to type 2 diabetes, given its ability to improve glucose metabolism and reduce insulin resistance.

5. Improved Quality of Life

  • Overall Well-being: Patients using Tirzepatide often report an improved quality of life due to better control over blood sugar levels, weight loss, and potentially reduced medication burden if Tirzepatide can replace other diabetes medications.
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