Polyethylene Glycol 3350 (PEG75, Macrogol 3350, Powder)
- Product Code: 34239
For use as excipients in food/drug/cosmetics
Appearance: Powder
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Test Name | Specification |
---|---|
Appearance (25?) (EP) | White or almost white solid with a waxy or paraffin-like appearance. Very soluble in water and in methylene chloride, very sligh |
Identification (EP/A) | Conforms to EP |
Identification (EP/B) | Conforms to EP |
Identification (EP/C) | Conforms to EP |
Definition (USP/A) | Qualified to USP |
Definition (USP/B) | Qualified to USP |
Definition (USP) | 97.0-103.0% |
Appearance of solution (EP) | Meet requirements |
Completeness and Color of Solution (USP) | Meet requirements |
Acidity or Alkalinity (EP) | Meet requirements |
Acidity and Alkalinity (USP) | 4.5-7.5 |
Average Molecular Weight (EP) | 3015-3685 |
Polydispersity (USP) | 90%-110% |
Ethylene Glycol (USP) | 0.062 Max |
Kinematic viscosity (mm | 76-110 |
Freezing point (?) (EP) | 53-57 |
Sum of diethylene and ethylene glycol (%) (USP) | 0.2 Max |
Sum of Formaldehyde and Acetaldehyde (?g/g) (USP) | 200 Max |
Hydroxyl value (EP) | 30-38 |
Reducing substances (EP) | Meet requirements |
Formaldehyde (ppm) (EP) | 30 Max |
Formaldehyde (ppm) (USP) | 30 Max |
Ethylene oxide (ppm) (EP) | 1 Max |
Dioxan (ppm) (EP) | 10 Max |
Free Ethylene Oxide (?g/g) (USP) | 10 Max |
1,4-Dioxane (?g/g) (USP) | 10 Max |
Water (%) (EP) | 1 Max |
Sulfated ash (%) (EP) | 0.2 Max |
Residue on Ignition (%) (USP) | 0.1 Max |
Polyethylene Glycol 3350 (PEG 3350), also known as Macrogol 3350, is a polymer used primarily in pharmaceuticals but also finds applications in cosmetics and, to a lesser extent, in food. Here is a detailed look at its uses:
Use in Cosmetics
While PEG 3350 is not as commonly used in cosmetics as some other PEGs, it still serves important functions:
- Humectant: Helps retain moisture in the skin, aiding in hydration and smoothness.
- Solvent: Facilitates the dissolution of other ingredients, ensuring a consistent formulation.
- Thickening Agent: Improves the viscosity and texture of cosmetic products.
- Stabilizer: Maintains the stability and consistency of formulations, preventing separation.
Use in Food
PEG 3350 is rarely used in food products. When it is, it functions in roles similar to other PEGs:
- Antifoaming Agent: Reduces foam during the processing of certain food products.
- Glazing Agent: Provides a shiny finish to some food items.
- Thickener and Stabilizer: Enhances the texture and stability of processed foods.
Use in Pharmaceuticals
PEG 3350 is primarily known for its pharmaceutical applications, especially as a laxative:
- Laxative: Used to treat constipation by increasing the water content in the stool, making it easier to pass. It is a common ingredient in over-the-counter and prescription laxatives.
- Excipient: Serves as a carrier or medium for active pharmaceutical ingredients, aiding in their proper delivery and absorption.
- Binder: Helps form tablets by binding ingredients together, ensuring uniformity and stability.
- Solubilizer: Enhances the solubility of drugs with poor water solubility, improving their bioavailability.
Usage: Used in cosmetics/food/drug.
Product appearance: white powder
Solubility: Can be dissolved in water directly.
Storage: For long-term storage Store in the refrigerator. Do not expose to sunlight or heat. Seal the lid tightly. Shelf life is at least 2 years.
INCI: PEG-75
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For use as excipients in food/drug/cosmetics
Appearance: Powder
Polyethylene Glycol 3350 (PEG 3350), also known as Macrogol 3350, is a polymer used primarily in pharmaceuticals but also finds applications in cosmetics and, to a lesser extent, in food. Here is a detailed look at its uses:
Use in Cosmetics
While PEG 3350 is not as commonly used in cosmetics as some other PEGs, it still serves important functions:
- Humectant: Helps retain moisture in the skin, aiding in hydration and smoothness.
- Solvent: Facilitates the dissolution of other ingredients, ensuring a consistent formulation.
- Thickening Agent: Improves the viscosity and texture of cosmetic products.
- Stabilizer: Maintains the stability and consistency of formulations, preventing separation.
Use in Food
PEG 3350 is rarely used in food products. When it is, it functions in roles similar to other PEGs:
- Antifoaming Agent: Reduces foam during the processing of certain food products.
- Glazing Agent: Provides a shiny finish to some food items.
- Thickener and Stabilizer: Enhances the texture and stability of processed foods.
Use in Pharmaceuticals
PEG 3350 is primarily known for its pharmaceutical applications, especially as a laxative:
- Laxative: Used to treat constipation by increasing the water content in the stool, making it easier to pass. It is a common ingredient in over-the-counter and prescription laxatives.
- Excipient: Serves as a carrier or medium for active pharmaceutical ingredients, aiding in their proper delivery and absorption.
- Binder: Helps form tablets by binding ingredients together, ensuring uniformity and stability.
- Solubilizer: Enhances the solubility of drugs with poor water solubility, improving their bioavailability.
Usage: Used in cosmetics/food/drug.
Product appearance: white powder
Solubility: Can be dissolved in water directly.
Storage: For long-term storage Store in the refrigerator. Do not expose to sunlight or heat. Seal the lid tightly. Shelf life is at least 2 years.
INCI: PEG-75
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