Polyethylene Glycol 3350 (PEG75, Macrogol 3350, Powder)

  • Product Code: 34239

For use as excipients in food/drug/cosmetics

Appearance: Powder

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Test Name Specification
Appearance (25?) (EP) White or almost white solid with a waxy or paraffin-like appearance. Very soluble in water and in methylene chloride, very sligh
Identification (EP/A) Conforms to EP
Identification (EP/B) Conforms to EP
Identification (EP/C) Conforms to EP
Definition (USP/A) Qualified to USP
Definition (USP/B) Qualified to USP
Definition (USP) 97.0-103.0%
Appearance of solution (EP) Meet requirements
Completeness and Color of Solution (USP) Meet requirements
Acidity or Alkalinity (EP) Meet requirements
Acidity and Alkalinity (USP) 4.5-7.5
Average Molecular Weight (EP) 3015-3685
Polydispersity (USP) 90%-110%
Ethylene Glycol (USP) 0.062 Max
Kinematic viscosity (mm 76-110
Freezing point (?) (EP) 53-57
Sum of diethylene and ethylene glycol (%) (USP) 0.2 Max
Sum of Formaldehyde and Acetaldehyde (?g/g) (USP) 200 Max
Hydroxyl value (EP) 30-38
Reducing substances (EP) Meet requirements
Formaldehyde (ppm) (EP) 30 Max
Formaldehyde (ppm) (USP) 30 Max
Ethylene oxide (ppm) (EP) 1 Max
Dioxan (ppm) (EP) 10 Max
Free Ethylene Oxide (?g/g) (USP) 10 Max
1,4-Dioxane (?g/g) (USP) 10 Max
Water (%) (EP) 1 Max
Sulfated ash (%) (EP) 0.2 Max
Residue on Ignition (%) (USP) 0.1 Max

Polyethylene Glycol 3350 (PEG 3350), also known as Macrogol 3350, is a polymer used primarily in pharmaceuticals but also finds applications in cosmetics and, to a lesser extent, in food. Here is a detailed look at its uses:

Use in Cosmetics

While PEG 3350 is not as commonly used in cosmetics as some other PEGs, it still serves important functions:

  • Humectant: Helps retain moisture in the skin, aiding in hydration and smoothness.
  • Solvent: Facilitates the dissolution of other ingredients, ensuring a consistent formulation.
  • Thickening Agent: Improves the viscosity and texture of cosmetic products.
  • Stabilizer: Maintains the stability and consistency of formulations, preventing separation.

Use in Food

PEG 3350 is rarely used in food products. When it is, it functions in roles similar to other PEGs:

  • Antifoaming Agent: Reduces foam during the processing of certain food products.
  • Glazing Agent: Provides a shiny finish to some food items.
  • Thickener and Stabilizer: Enhances the texture and stability of processed foods.

Use in Pharmaceuticals

PEG 3350 is primarily known for its pharmaceutical applications, especially as a laxative:

  • Laxative: Used to treat constipation by increasing the water content in the stool, making it easier to pass. It is a common ingredient in over-the-counter and prescription laxatives.
  • Excipient: Serves as a carrier or medium for active pharmaceutical ingredients, aiding in their proper delivery and absorption.
  • Binder: Helps form tablets by binding ingredients together, ensuring uniformity and stability.
  • Solubilizer: Enhances the solubility of drugs with poor water solubility, improving their bioavailability.

Usage: Used in cosmetics/food/drug.

Product appearance: white powder

Solubility: Can be dissolved in water directly.

Storage: For long-term storage Store in the refrigerator. Do not expose to sunlight or heat. Seal the lid tightly. Shelf life is at least 2 years.

INCI: PEG-75




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Polyethylene Glycol 3350 (PEG75, Macrogol 3350, Powder)

For use as excipients in food/drug/cosmetics

Appearance: Powder

Polyethylene Glycol 3350 (PEG 3350), also known as Macrogol 3350, is a polymer used primarily in pharmaceuticals but also finds applications in cosmetics and, to a lesser extent, in food. Here is a detailed look at its uses:

Use in Cosmetics

While PEG 3350 is not as commonly used in cosmetics as some other PEGs, it still serves important functions:

  • Humectant: Helps retain moisture in the skin, aiding in hydration and smoothness.
  • Solvent: Facilitates the dissolution of other ingredients, ensuring a consistent formulation.
  • Thickening Agent: Improves the viscosity and texture of cosmetic products.
  • Stabilizer: Maintains the stability and consistency of formulations, preventing separation.

Use in Food

PEG 3350 is rarely used in food products. When it is, it functions in roles similar to other PEGs:

  • Antifoaming Agent: Reduces foam during the processing of certain food products.
  • Glazing Agent: Provides a shiny finish to some food items.
  • Thickener and Stabilizer: Enhances the texture and stability of processed foods.

Use in Pharmaceuticals

PEG 3350 is primarily known for its pharmaceutical applications, especially as a laxative:

  • Laxative: Used to treat constipation by increasing the water content in the stool, making it easier to pass. It is a common ingredient in over-the-counter and prescription laxatives.
  • Excipient: Serves as a carrier or medium for active pharmaceutical ingredients, aiding in their proper delivery and absorption.
  • Binder: Helps form tablets by binding ingredients together, ensuring uniformity and stability.
  • Solubilizer: Enhances the solubility of drugs with poor water solubility, improving their bioavailability.

Usage: Used in cosmetics/food/drug.

Product appearance: white powder

Solubility: Can be dissolved in water directly.

Storage: For long-term storage Store in the refrigerator. Do not expose to sunlight or heat. Seal the lid tightly. Shelf life is at least 2 years.

INCI: PEG-75

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