Standardized Terpinen-4-ol from Tea Tree Extract, developed for anti-acne formulation

with Terpinen-4-ol purity higher than 98%

Acne-TT™ (Standardized Terpinen-4-ol from Tea Tree Extract, developed for anti-acne formulation)

with Terpinen-4-ol purity higher than 98%, compared to regular tea tree oil that normally contain less than 30%

Terpinen-4-ol is a major active component of tea tree oil, which has been widely used for its antimicrobial and anti-inflammatory properties. It is particularly effective as a topical treatment for acne due to its ability to reduce inflammation and fight bacteria.

Mechanism of Action

1. Antimicrobial Properties:
   
   

   • Terpinen-4-ol exhibits strong antimicrobial activity against a variety of bacteria, fungi, and viruses.
   • It is effective against Propionibacterium acnes, the bacteria commonly associated with acne.
     
     

2. Anti-Inflammatory Properties:
   
   

   • It helps reduce the inflammation associated with acne lesions.
   • By decreasing inflammatory responses, it can help reduce redness and swelling.
     
     

3. Sebum Regulation:
   
   

   • It may help in regulating sebum production, which is often a contributing factor to acne.

Clinical Evidence

Several studies have demonstrated the efficacy of terpinen-4-ol and tea tree oil in treating acne:

• Comparative Studies: Tea tree oil has been shown to be as effective as benzoyl peroxide, a commonly used acne treatment, but with fewer side effects such as dryness, irritation, and peeling.
  
  
• Topical Gels and Solutions: Products containing terpinen-4-ol or tea tree oil can significantly reduce the number and severity of acne lesions over time.

Usage: For anti-acne products

Mixing method: Mix in oil

Usage rate: 0.1-0.5%

Product appearance: Clear liquid with natural tea tree odor

Solubility: Can dissolve in oil, cannot dissolve in water

Storage: Store in the refrigerator (5-10 degrees). Do not expose to light and heat. Shelf life is at least 24 months from the date of production.

INCI Name : Melaleuca Alternifolia Leaf Extract

(standardized Terpinen-4-ol purity higher than 98%)