Hexylresorcinol AF (e.q. Hentowhite)

  • Product Code: 125958

a water soluble version of 4-Hexylresorcinol, is an alkylresorcinol with many skin benefits

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Test Name Specification
ASPECT Syrup
COLOUR Amber
MICROBIOLOGICAL CONTROL < 50 CFU/g (Total germs)
MICROBIOLOGICAL CONTROL (Pathogens) Absence
ULTRA-VIOLET SPECTRUM (Alcohol sol. 0.05%) Conforms to standard
INFRA-RED SPECTRUM Conforms to standard
REFRACTIVE INDEX (20°C) 1.465-1.485
DENSITY (20°C) 0.980-1.200 g/ml
ACIDITY INDEX 15.00-25.00 mg KOH/g
PEROXIDE INDEX 10.00 meq O2/kg Max
IODINE INDEX (Wij) 20.00-35.00 gl2/100 g
SOLUBILITY (Ethanol) Transparent solution
SOLUBILITY (Glycerin or Propylene Glycol) Whitish solution
SOLUBILITY (Water) Transparent solution

Hexylresorcinol AF is a water soluble version of 4-Hexylresorcinol, is an alkylresorcinol with many skin benefits:

  • Whitening Care
  • Age-spot treatment
  • Photo-aging, brightening/lightening Care
  • Underarm and bikini area spots
  • Ethnic skin Care

Description:

Hexylresorcinol AF is a naturally effective cosmetic ingredient for the reduction of skin dark spots and skin whitening, without irritation effects. It has a significant reducing effect on tyrosinase activity and works synergistically on the three stages of the melanogenesis process:

  1. Before melanin synthesis: Interferes in the synthesis and glycosylation of tyrosinase, preventing its absorption by the melanosome.
  2. During melanin synthesis: Acts as a competitive inhibitor of tyrosinase, also affecting TRP1 and TRP2 enzymes, reducing melanogenesis-promoting byproducts.
  3. After melanin synthesis: Enhances tyrosinase degradation, inhibits melanosome transfer to keratinocytes, and offers light peeling thanks to the fatty acids.

Benefits:

  • Decreases melanin formation at the early stage of synthesis
  • Reduces melanin synthesis and tyrosinase activity in skin melanocytes
  • Reduces melanosome transfer to keratinocytes
  • Promotes desquamation of superficial horny layers and melanin pigmentary residues
  • Non-irritating effect

Clinical Efficacy Tests:

1. Whitening Effect:

Melanin synthesis inhibition vs Hydroquinone on melanocyte cell culture.

2. Tyrosinase Inhibition:

Spectrophotometric assay vs Kojic acid and Hydroquinone - 100% inhibition at 0.001%.

3. In-Vivo Whitening Efficacy:

20 volunteers, T=4 weeks - 94.6% inhibition (0.15 mg/L Hexylresorcinol AF).

 

Usage: Ingredients in any whitening formulation

Mixing method: Soluble in water

Usage rate: 1-3%

Product characteristics: Clear transparent light colored liquid

Solubility: Can dissolve in water

Storage: Shelf life: 24 months, stored at cold temperature. Avoid sunlight and heat.

 

INCI Name : Polysorbate 20, Hexylresorcinol, Caprylic Acid, Isopropyl alcohol, Peg-400, Caproic Acid, Capric Acid.




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Hexylresorcinol AF (e.q. Hentowhite)

a water soluble version of 4-Hexylresorcinol, is an alkylresorcinol with many skin benefits

Hexylresorcinol AF is a water soluble version of 4-Hexylresorcinol, is an alkylresorcinol with many skin benefits:

  • Whitening Care
  • Age-spot treatment
  • Photo-aging, brightening/lightening Care
  • Underarm and bikini area spots
  • Ethnic skin Care

Description:

Hexylresorcinol AF is a naturally effective cosmetic ingredient for the reduction of skin dark spots and skin whitening, without irritation effects. It has a significant reducing effect on tyrosinase activity and works synergistically on the three stages of the melanogenesis process:

  1. Before melanin synthesis: Interferes in the synthesis and glycosylation of tyrosinase, preventing its absorption by the melanosome.
  2. During melanin synthesis: Acts as a competitive inhibitor of tyrosinase, also affecting TRP1 and TRP2 enzymes, reducing melanogenesis-promoting byproducts.
  3. After melanin synthesis: Enhances tyrosinase degradation, inhibits melanosome transfer to keratinocytes, and offers light peeling thanks to the fatty acids.

Benefits:

  • Decreases melanin formation at the early stage of synthesis
  • Reduces melanin synthesis and tyrosinase activity in skin melanocytes
  • Reduces melanosome transfer to keratinocytes
  • Promotes desquamation of superficial horny layers and melanin pigmentary residues
  • Non-irritating effect

Clinical Efficacy Tests:

1. Whitening Effect:

Melanin synthesis inhibition vs Hydroquinone on melanocyte cell culture.

2. Tyrosinase Inhibition:

Spectrophotometric assay vs Kojic acid and Hydroquinone - 100% inhibition at 0.001%.

3. In-Vivo Whitening Efficacy:

20 volunteers, T=4 weeks - 94.6% inhibition (0.15 mg/L Hexylresorcinol AF).

 

Usage: Ingredients in any whitening formulation

Mixing method: Soluble in water

Usage rate: 1-3%

Product characteristics: Clear transparent light colored liquid

Solubility: Can dissolve in water

Storage: Shelf life: 24 months, stored at cold temperature. Avoid sunlight and heat.

 

INCI Name : Polysorbate 20, Hexylresorcinol, Caprylic Acid, Isopropyl alcohol, Peg-400, Caproic Acid, Capric Acid.

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