Acne treatment technology that was developed From the research findings that Restoration of the skin's protective layer (skin-barrier) combined with treating acne with the original technique of killing acne bacteria (P. Acnes) will help the treatment efficiency be better than other techniques and provide sustainable results.

AcnePLEX™ acne treatment technology that was developed From the research findings that Restoration of the skin's protective layer (skin-barrier) combined with treating acne with the original technique of killing acne bacteria (P. Acnes) will help the treatment efficiency be better than other techniques and provide sustainable results. Providing lasting acne treatment results when used continuously for at least 60 days, twice daily, is a highlight of AcnePLEX™ compared to other acne treatment ingredients or medicines.

AcnePLEX™ mechanism of action

1. Restoring the balance of the skin barrier. (skin-barrier) with ceramides and phytosphingosine which is a natural component of the skin layer

The research found that the levels of Ceramides and phytosphingosine is at a low level In acne-prone skin due to (1) levels of Ceramides and phytosphingosine enough of the skin It helps the natural skin cell exfoliation mechanism. can work well natural skin cell turnover It is a very important process. To reduce the chance of comedone blockage which is the beginning of acne (2) phytosphingosine according to the nature of the skin act as anti-inflammatory and anti-bacteria Therefore it is extremely important. In the process of fighting P.Acnes, research has found that When the skin is level phytosphingosine that is normal for the formation of acne bacteria As well as the inflammation that turns into acne, it is difficult to do.

2. Royal Jelly extract (10-hydroxydecanoic acid) acts as an anti-bacteria. which until now There is a lot of research on the effectiveness of anti-bacteria As a result, the growth of P.Acnes is more difficult.

3. Salicylic Acid is considered a standard component that It is medically accepted that it can help treat acne well. Works to kill acne. and exfoliate skin cells to help reduce the chance of comedone blockage, but usually there are limitations to its use With a nature that irritates the skin And when there is an imbalance of the skin-barrier, it causes new acne to appear. which has been adjusted to solve this problem in AcnePLEX™ which has a balance of components that Both help strengthen the skin's protective barrier. Go along with treating acne.

Recommendations for formula development using AcnePLEX™ as an ingredient

1. AcnePLEX™ was developed to have a positive charge. In order to be able to stick to the skin well and has long-lasting effects But there are limitations in compatibility with formulas that include cream maker or gel maker that are negatively charged. In formulas that require a viscous consistency Is it a gel or cream? You must choose to use a non-ionic gel maker only (such as HEC , HPMC ).

2. AcnePLEX™ may produce white foam when spread onto the skin. Therefore, it is recommended to use X-Foam to prevent foaming in the formula.

3. AcnePLEX™ can be used together with As usual with other acne treatment ingredients, using AcnePLEX™ at 4% is sufficient to treat normal acne and 5.5% is sufficient to treat severe acne. There is no need to use any additional ingredients.

AcnePLEX™ contains 35% Salicylic Acid.

Example of acne treatment gel formula with AcnePLEX™ 5%

AcnePLEX™ 5%

Hydroxypropyl Methylcellulose 1%

Mild Preserved Eco 1%

X-Foam 0.5%

The remaining water should be 100% complete.

Usage: For products intended to treat acne.

Mixing method: Mix in water. Can withstand heat not exceeding 80 degrees.

Usage rate: 1-5.5% (4% for general acne, 5.5% for severe acne)

Product appearance: clear, yellow liquid

Solubility: Can dissolve in water

Storage: Can be stored at room temperature. But close the bottle cap tightly. Then completely protected from sunlight or heat. The product has a minimum shelf life of 2 years.