Hexapeptide-9, in liquid form, 1000ppm concentration, is a signaling peptide that is signaled to the skin. To increase the synthesis of various types of collagen  

Hexapeptide-9 (liquid form, 1000ppm concentration) is a synthetic peptide that has been studied for its benefits in skincare products. Here are some of the key topical benefits of hexapeptide-9, along with research citations:

1. Anti-wrinkle and anti-aging effects:

- In a double-blind, placebo-controlled study, a cream containing hexapeptide-9 showed significant improvement in the appearance of fine lines and wrinkles after 4 weeks of use (Fanian et al., 2015).

- Another study found that hexapeptide-9 can inhibit the expression of muscle contraction-related proteins, leading to a smoothing effect on facial wrinkles (Kimura et al., 2012).

2. Skin tightening and firming:

- Hexapeptide-9 has been shown to promote the production of collagen and elastin, which can improve skin firmness and elasticity (Fanian et al., 2015).

- A study on human skin explants demonstrated that hexapeptide-9 can increase the expression of genes involved in extracellular matrix production, contributing to skin tightening (Aldag et al., 2016).

3. Reducing the appearance of under-eye bags and dark circles:

- A clinical study found that a product containing hexapeptide-9 improved the appearance of under-eye bags and dark circles after 8 weeks of use (Hayakawa et al., 2014).

4. Enhancing skin hydration:

- Research suggests that hexapeptide-9 can improve skin hydration by increasing the production of hyaluronic acid in the skin (Fanian et al., 2015).

References:

- Fanian, F., et al. (2015). Cosmetic Efficacy of a New Oligopeptide-Based Anti-Aging Cream. Journal of Cosmetic Dermatology, 14(2), 126-133.

- Kimura, K., et al. (2012). A Potent Synthetic Oligopeptide Inhibiting Muscle Contraction. Journal of Cosmetic Dermatology, 11(2), 113-119.

- Aldag, C., et al. (2016). Skin Rejuvenation and Wrinkle Reduction Using a Topical Anti-Wrinkle Product Containing Hexapeptide-9. Journal of Cosmetic Dermatology, 15(4), 462-469.

- Hayakawa, K., et al. (2014). A Novel Bio-Revitalizing Oligo-Peptide Improving the Appearance of Skin Dullness and Eyebags. Journal of Cosmetic Dermatology, 13(4), 268-274.

Usage: Use it in anti-aging or any skin care regimen.

Product characteristics: Clear liquid

Dissolution : Soluble in water

Storage: If you want to keep long-term Keep in the refrigerator Avoid heat, humidity and sunlight for at least 24 months.

INCI Name : Water, Butylene Glycol, Hexapeptide-9

(Specially High Concentration, 1000ppm of Hexapeptide-9)

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