A natural substance found in fish and human nerve tissue. Can reduce wrinkles, tighten skin, fight free radicals. It also helps enhance the efficiency of other antioxidants. Provides good performance at an affordable price

DMAE (Dimethylaminoethanol), an important ingredient of all Dr.Perricone ( Perricone MD ) anti-wrinkle products, is a natural substance. Helps stimulate synthesis phosphatidylcholine (An important component of cell membranes) found in abundance in fish and human nerve tissue. Can reduce wrinkles, tighten skin, fight free radicals. It also helps enhance the efficiency of other antioxidants.

DMAE (SkinTight MD™) Liquid undergoes a process To reduce the smell of the ingredients (deodorization) of DMAE, which has a strong odor and adjusts the pH so that it can be mixed into any formula immediately.

Using DMAE in wrinkle reduction formulas Results are usually visible after approximately 10 days of continuous use. Suitable for use in conjunction with other wrinkle-reducing peptides. To help enhance efficiency and make results faster and clearer

DMAE is suitable for use with Vitamin B5 , increasing efficiency when used together.

Precautions for using DMAE

Although DMAE is highly effective in reducing wrinkles, Lift and tighten facial skin But there is a disadvantage. Not suitable for use on thin, sensitive skin because DMAE can irritate the skin. When used in high concentrations Therefore, to reduce the risk of allergies and skin irritation. It should not be used at the maximum level recommended by the manufacturer. For beginners Should be used at a level not exceeding half. of the highest level recommended by the manufacturer. In addition, adding irritation-reducing ingredients to formulas that contain DMAE will help reduce irritation caused by DMAE.

Usage: Can be used in all forms of anti-aging cosmetic formulas.

Mixing method: Mix in the final step. The temperature of cosmetics must be lower than 40 °C.

Usage rate: 1-10% (recommended 3%, use above 5% may irritate the skin. and makes it very icky)

Product characteristics: Clear liquid with a characteristic odor.

Solubility: Can dissolve in water

Storage: Store at room temperature. Do not expose to heat. If you want to keep it long term Can be stored in a cool place, temperature 6-8 degrees, has a shelf life of 2 years.

INCI Name : DIMETHYLAMINOETHANOL TARTRATE (concentration 50% as Bitartrate form)

Example of Toner DMAE formula

remaining distilled water

DMAE (SkinTight MD™) Liquid 5-10%

Preservative 0.5%

Results from research

Research article: Skin Res Technol. 2002 Aug;8(3):164-7. Split face study on the cutaneous tensile effect of 2-dimethylaminoethanol (deanol) gel. Uhoda I, Faska N, Robert C, Cauwenbergh G, Piérard GE. Unit of Dermocosmetology, Department of Dermatopathology, University Medical Center of Liège, CHU Sart Tilman, B-4000 Liège, Belgium.

Conclusion: DMAE is effective in increasing skin firmness.

Research article: Am J Clin Dermatol. 2005;6(1):39-47. The role of dimethylaminoethanol in cosmetic dermatology. Grossman R. Johnson and Johnson Consumer Products Worldwide, Skillman, NJ 08558, USA.

Summary of results: Using DMAE Gel, 3% concentration, for 16 weeks can reduce wrinkles on the forehead and eye lines.

Research article: Br J Dermatol. 2007 Mar;156(3):433-9. The antiwrinkle effect of topical concentrated 2-dimethylaminoethanol involves a vacuolar cytopathology. Morissette G, Germain L, Marceau F. Center de Recherche en Rhumatologie et Immunologie, Center Hospitalier Universitaire de Québec, Québec QC, Canada.

Summary of results: Using DMAE at a concentration of 3% resulted in thicker epidermis and reduced wrinkles.

Research article: Phytomedicine. 2007 Nov;14(11):711-5. Randomised, placebo-controlled, double-blind, split-face study on the clinical efficacy of Tricutan on skin firmness. Sommerfeld B. Dermatology Clinic, Danavägen 7B, SE-18131 Lidingö, Sweden. bea.hudmontt@telia.com

Summary of results: From an experiment with a group of 25 female users, DMAE can help tighten the skin. and increases the elasticity (elasticity) of the skin

Research article: Pharmazie. 2009 Dec;64(12):818-22. In vivo skin effects of a dimethylaminoethanol (DMAE) based formulation. Tadini KA, Campos PM. Department of Pharmaceutical Sciences, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, University of São Paulo, Brazil. ktadini@fcfrp.usp.br.

Conclusion: DMAE can increase the thickness of collagen. Thickens the epidermis and increases skin moisture (hydrating) after 8 weeks of continuous use.

Examples of products using DMAE as the main ingredient

Perricone MD's Anti-aging products use DMAE as the main ingredient in all of them.