Research shows sclareol has potent anti-photoaging effects, making it an excellent candidate ingredient for skincare products aimed at reducing the visible signs of skin aging

Here is a marketing-oriented scientific summary of the key points about sclareol from the research paper:

Sclareol: An Effective Botanical Ingredient for Improving Skin Aging and Wrinkles

Please see detail anti-wrinkle effect on the attached research paper.

- Sclareol is a naturally-derived compound isolated from the plant Salvia officinalis (sage). It has a history of use in the cosmetic and fragrance industries.

- Research shows sclareol has potent anti-photoaging effects, making it an excellent candidate ingredient for skincare products aimed at reducing the visible signs of skin aging.

- In human skin cells and 3D skin models, sclareol:

  - Stimulated cell proliferation and protected against UV-induced cell death
  - Inhibited the expression of key matrix metalloproteinase (MMP) enzymes that degrade collagen and contribute to wrinkle formation
  - Reduced activation of the AP-1 transcription factor that regulates MMPs
  - Helped maintain epidermal thickness and stimulated growth of new skin cells after UV exposure

- In a clinical study, a 0.02% sclareol-containing cream significantly improved the appearance of facial wrinkles around the eyes after 12 weeks of use, with no adverse effects.

The scientific data demonstrates sclareol's efficacy as an anti-aging botanical active. Its ability to protect against UV-induced skin damage and visibly reduce wrinkles makes it a valuable addition to cosmetic formulations targeting signs of skin aging. Formulators can leverage sclareol's unique properties to develop high-performing, natural-origin anti-aging skincare products.

Usage rate: 0.1-0.2%

Product appearance: white/light color powder It has a natural smell.

Solubility: Can be dissolved in oil, glycol, alcohol.

Storage: Store in a cool place. Do not expose to light and heat. At least 24 months old

INCI Name : Sclareol