Pure-Melatonin™ (Odorless, White Powder)

  • Product Code: 867

Pure Melatonin It has a powerful anti-oxidant effect, helps extend the life of outer skin cells , controls the function of collagenases , can help inhibit skin redness (etythema) when damaged by UV light , stimulates hair growth, reduces hair loss.

Special grade, white powder, not yellow, with a special production process without using Fermentation.

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Test Name Specification
CHARACTERISTICS WHITE or OFF-WHITE CRYSTALLINE POWDER
IDENTIFICATION INFRARED ABSORPTION / ULTRAVIOLET ABSORPTION / HPLC IDENTIFICATION TEST
MELTING POINT °C 116-120
ASSAY (On dry basis) % 98.5-101.5
INDIVIDUAL IMPURITIES % NMT 0.1
TOTAL IMPURITIES % NMT 0.5
LOSS ON DRYING % NMT 0.5
RESIDUE ON IGNITION % NMT 0.1
CHLORIDE % NMT 0.02
RESIDUAL SOLVENTS ppm NMT 1000
HEAVY METALS ppm NMT 10
Pb ppm NMT 2.0
As ppm NMT 1.0
Cd ppm NMT 1.0
Hg ppm NMT 0.1
TOTAL AEROBIC BACTERIA CFU/g NMT 1000
YEAST & MOLD CFU/g NMT 50
COLIFORM GROUP MPN/g NMT 0.92
E.Coli /g ABSENT/25
SALMONELLA /g ABSENT/25
STAPHYLOCOCCUS /g ABSENT/25

Pure-Melatonine™ - Pure Melatonin

Melatonin has a powerful anti-oxidant effect compared to other antioxidants. It also has a prominent feature in terms of its good absorption into the skin. Due to its lipophilic nature (compatible with oils), when it is on the skin layers, it can be absorbed well. It is currently popularly used as an ingredient in the anti-aging group for the skin.

In addition, there are research results in the past 10 years for the benefits of Melatonin for the skin, which found the following benefits:

Proliferation of keratinocytes (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914270/ , https://iv.iiarjournals.org/content/23/5/739.full) or helping to extend the life of outer skin cells, making the skin have a better protective barrier (improve skin barrier).

Melatonin downregulates collagenases including MMP-1, MMP-3 and MMP-10 (https://www.researchgate.net/publication/45100000). It controls the activity of collagenases, enzymes that break down collagen, making the collagen under the skin last longer.

Melatonin suppresses erythema when applied before UV exposure (https://www.researchgate.net/publication/232451181). It can help suppress skin redness (etythema) when exposed to UV light.

Topical Melatonin for Treatment of Androgenetic Alopecia Melatonin stimulates hair growth and reduces hair loss.

The experimental results (Reference: Int J Trichology. 2012 OctDec; 4(4): 236–245. Research name: Topical Melatonin for Treatment of Androgenetic Alopecia Tobias W Fischer, Ralph M Trüeb, Gabriella Hänggi, Marcello Innocenti, and Peter Elsner ) found that the use of Melatonin at a concentration of 0.1% reduced hair loss and stimulated hair growth in 48.2% of all users after 90 days of continuous use, and continued to improve after 180 days of continuous use in 32.1% of all users.

(Please see the research results in the attached brochure)

IMPORTANT: Melatonin is sensitive to air. Continuous exposure to air will deteriorate. Finished products that use Melatonin as an ingredient must be protected from air. For example, package the finished product in a vacuum tube. Do not pack the product in a jar where the formula can be continuously exposed to air (continuous exposure to air can cause Melatonin to deteriorate by more than 60% after continuous exposure to air for 15 days).

Usage: For any skin care products, for hair care/hair growth products.

Method of mixing: Mix into the formula in the final step. Avoid prolonged exposure to air and the pH of the formula must be in the range of 4-10 and do not expose to heat.

Usage rate: 0.1-3%

Product appearance: white powder

Solubility: Soluble in some oils and some glycols (e.g. ethoxydiglycol), 1,3-Propanediol.

Storage: Keep in a refrigerator at 5-10 degrees Celsius. Avoid exposure to sunlight, heat, air. Seal the lid tightly. Shelf life is at least 2 years.

INCI Name : Melatonin

Examples of products that use Melatonin as a main ingredient in their formulas



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Pure-Melatonin™ (Odorless, White Powder)

Pure Melatonin It has a powerful anti-oxidant effect, helps extend the life of outer skin cells , controls the function of collagenases , can help inhibit skin redness (etythema) when damaged by UV light , stimulates hair growth, reduces hair loss.

Special grade, white powder, not yellow, with a special production process without using Fermentation.

Pure-Melatonine™ - Pure Melatonin

Melatonin has a powerful anti-oxidant effect compared to other antioxidants. It also has a prominent feature in terms of its good absorption into the skin. Due to its lipophilic nature (compatible with oils), when it is on the skin layers, it can be absorbed well. It is currently popularly used as an ingredient in the anti-aging group for the skin.

In addition, there are research results in the past 10 years for the benefits of Melatonin for the skin, which found the following benefits:

Proliferation of keratinocytes (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914270/ , https://iv.iiarjournals.org/content/23/5/739.full) or helping to extend the life of outer skin cells, making the skin have a better protective barrier (improve skin barrier).

Melatonin downregulates collagenases including MMP-1, MMP-3 and MMP-10 (https://www.researchgate.net/publication/45100000). It controls the activity of collagenases, enzymes that break down collagen, making the collagen under the skin last longer.

Melatonin suppresses erythema when applied before UV exposure (https://www.researchgate.net/publication/232451181). It can help suppress skin redness (etythema) when exposed to UV light.

Topical Melatonin for Treatment of Androgenetic Alopecia Melatonin stimulates hair growth and reduces hair loss.

The experimental results (Reference: Int J Trichology. 2012 OctDec; 4(4): 236–245. Research name: Topical Melatonin for Treatment of Androgenetic Alopecia Tobias W Fischer, Ralph M Trüeb, Gabriella Hänggi, Marcello Innocenti, and Peter Elsner ) found that the use of Melatonin at a concentration of 0.1% reduced hair loss and stimulated hair growth in 48.2% of all users after 90 days of continuous use, and continued to improve after 180 days of continuous use in 32.1% of all users.

(Please see the research results in the attached brochure)

IMPORTANT: Melatonin is sensitive to air. Continuous exposure to air will deteriorate. Finished products that use Melatonin as an ingredient must be protected from air. For example, package the finished product in a vacuum tube. Do not pack the product in a jar where the formula can be continuously exposed to air (continuous exposure to air can cause Melatonin to deteriorate by more than 60% after continuous exposure to air for 15 days).

Usage: For any skin care products, for hair care/hair growth products.

Method of mixing: Mix into the formula in the final step. Avoid prolonged exposure to air and the pH of the formula must be in the range of 4-10 and do not expose to heat.

Usage rate: 0.1-3%

Product appearance: white powder

Solubility: Soluble in some oils and some glycols (e.g. ethoxydiglycol), 1,3-Propanediol.

Storage: Keep in a refrigerator at 5-10 degrees Celsius. Avoid exposure to sunlight, heat, air. Seal the lid tightly. Shelf life is at least 2 years.

INCI Name : Melatonin

Examples of products that use Melatonin as a main ingredient in their formulas

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