pure melatonin It has a powerful anti-oxidant effect. It helps prolong the life of outer skin cells , controls the activity of collagenases , can help stop skin redness (etythema) when damaged by UV light , and stimulates hair growth. Reduce hair loss

Pure-Melatonine™ - Pure Melatonin

Melatonin has a powerful anti-oxidant effect compared to other types of antioxidants. It also has the advantage of being well absorbed into the skin. With the characteristics of being lipophillic (mixes well with oil) when on various surface layers. So it can be absorbed well. Nowadays, it is commonly used as an anti-aging ingredient for the skin.

In addition, there are research results during 10 years ago As for the various benefits of Melatonin on the skin, various benefits have been found as follows:

Proliferation of keratinocytes (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914270/ , https://iv.iiarjournals.org/content/23/5/739.full) or helping to extend lifespan of outer skin cells Makes the skin have a better protective barrier (improve skin barrier)

Melatonin downregulates collagenases including MMP-1, MMP-3 and MMP-10 (https://www.researchgate.net/publication/45100000). It controls the activity of collagenases, which are enzymes. that acts to degrade collagen Makes collagen under the skin Live longer

Melatonin suppresses erythema when applied before UV exposure (https://www.researchgate.net/publication/232451181) can help suppress redness of the skin (etythema) when damaged by UV light.

Topical Melatonin for Treatment of Androgenetic Alopecia Melatonin stimulates hair growth. Reduce hair loss

From the results of the experiment (Reference: Int J Trichology. 2012 OctDec; 4(4): 236–245. Name of the results: Topical Melatonin for Treatment of Androgenetic Alopecia Tobias W Fischer, Ralph M Trüeb, Gabriella Hänggi, Marcello Innocenti, and Peter Elsner ) found that using Melatonin at a concentration of 0.1% reduces hair loss symptoms. and stimulates hair growth in 48.2% of all users After using it for 90 consecutive days and getting better results continuously. After using for 180 consecutive days with 32.1% of all users

(Please see the research results in the brochure attachment)

IMPORTANT: Melatonin is sensitive to air when continuously exposed to air. will deteriorate in quality Finished products that use melatonin as an ingredient must be protected from the air, for example when packaging finished products. In a vacuum tube (vacuum tube). Do not pack the product in a jar. that the formula can be continuously exposed to air (Continuous exposure to air will cause Melatonin to deteriorate by more than 60% when exposed to air continuously for 15 days)

Usage: For any form of skin care product, for hair care/hair growth product.

How to mix: Mix into the formula. in the last step Avoid prolonged exposure to air and the pH of the formula must be in the range of 4-10 and do not expose to heat.

Usage rate: 0.1-3%

Product appearance: white powder

Solubility: soluble in some oils and some glycols (such as ethoxydiglycol), 1,3-Propanediol.

Storage: Store in the refrigerator, temperature 5-10 degrees. Do not expose to sunlight, heat, air. Seal the lid tightly. Shelf life is at least 2 years.

INCI Name : Melatonin

Examples of products that use Melatonin as the main component of the formula