EGCG is in microemulsion form. which can be dissolved in water directly and is highly effective in absorbing into the skin

Epigallocatechin Gallate (EGCG) is in microemulsion form. which can be dissolved in water directly and is highly effective in absorbing into the skin

Epigallocatechin Gallate has research results regarding various benefits to the skin as follows:

Helps synthesize Natural Moisturizing Amino Acids (NMFs):

Genes Expression: EGCG increases the expression of genes involved in the synthesis of Natural Moisturizing Factors (NMFs), including filaggrin (FLG), transglutaminase (TGM)-1, and hyaluronic acid synthesis. ก (HAS)-1, 2 and 3

Upregulation of FLG: EGCG significantly upregulates FLG levels. which is an important component in providing moisture to the skin

Effect on Upstream Proteins: This study investigated the effect of EGCG on upstream proteins, including MAPK and HAS-2. EGCG increased the phosphorylation of p38, ERK and JNK and the expression of HAS-2, indicating Regulation of NMF-related genes through MAPK


Helps retain moisture in the skin (Moisture Retention):

UVB-Induced Damage: EGCG reduces cell damage caused by UVB irradiation, indicating its protective activity against UV-induced skin damage.

HYAL Gene Expression: EGCG reduces gene expression. hyaluronidase (HYAL), specifically HYAL-4, under UVB-induced conditions. This suggests that EGCG inhibits the degradation of hyaluronic acid (HA) in the epidermis. As a result, the skin's ability to retain moisture increases.


Antioxidants:

Radical Scavenging: EGCG shows antioxidant effects by scavenging free radicals. This can be seen from its ability to reduce DPPH and ABTS radicals.

Intracellular ROS Regulation: EGCG regulates intracellular reactive oxygen species (ROS) levels in a dose-dependent manner. This indicates the ability to control both extracellular and intracellular radicals.

Quenching NO Production: EGCG quenches the production of nitric oxide (NO) caused by sodium nitroprusside (SNP), which also enhances its antioxidant properties.


Anti-cell death:

Caspase Cleavage Reduction: EGCG reduces the cleavage of caspase-3. which is a key molecule in significant cell death

Extrinsic Apoptotic Pathway Inhibition: EGCG selectively inhibits the formation of cleaved caspase-8, indicating extrinsic apoptotic pathway inhibition.


Helps whiten and brighten your skin:

Melanin Secretion Reduction: EGCG significantly reduces extracellular melanin secretion. especially at a concentration of 100 µM

Melanin Production Decrease: EGCG reduces melanin production in cells. This indicates its potential as a skin-whitening ingredient in cosmetics.

(Please study additional research results in the attached document)

From the test of absorption into the skin with Franz Cell, it was found that it was able to absorb more than 2 times better than normal at an application time of 8 hours.

Micromul™ EGCG Acid is a Microemulsion. with nano-level particle size with an average size of 1.7 nanometers

Usage: Used as an anti-oxidant to protect the skin from free radicals. or ingredients in the formula

Mixing method: Dissolve in water, avoid heat.

Usage Rate: 1-5% (Recommended 2-3% for anti-aging/anti-oxidant in skin care formulas)

Product appearance: clear liquid

Storage: For long-term storage Store at room temperature. Avoid exposure to sunlight, heat, and humidity. Close the lid tightly. Shelf life is at least 2 years.

INCI : Epigallocatechin Gallate, Water, Tween 80, Propylene Glycol, Isopropyl Myristate, Tocopheryl Acetate, 1,3-Propanediol, Ethylhexylglycerin.